Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38287 |
C3a Receptor Agonist
C3a receptor agonist 1,C3a受体激动剂,Complement 3a Receptor Agonist |
Complement System | Immunology/Inflammation |
C3a Receptor Agonist (C3a receptor agonist 1) 结合免疫系统补体途径中的G 蛋白偶联C3a 受体(C3aRs)。在肠缺血再灌注损伤模型中,C3aR 的激活可防止中性粒细胞动员。C3aRs 在成年小鼠的神经祖细胞和未成熟神经元上表达。C3a 在体外刺激神经祖细胞的分化。 | |||
TP2296L |
TLQP 21 acetate
|
Complement System | Immunology/Inflammation |
TLQP 21 acetate 是 G 蛋白偶联受体补体 3a 受体 1 (C3aR1) 的有效激动剂。 小鼠的 EC50 值为 10.3 μM,人的 EC50 值为 68.8 μM。它是一种 VGF 衍生肽,具有内分泌和内分泌特性。 | |||
T38077 |
TLQP-21 TFA
|
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TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions[1][2]. TLQP-21 TFA is a peptide of 21 amino acids. At a dose of 3 μM TLQP-21 induces up to ~69% of th... |